Platform Unit 1. Biomolecules Production

Platform Unit 1 supply biological molecules needed to the development of research projects framed in the strategic lines of Tissue Engineering, Intelligent Devices, Implants, and specially Therapeutic Nanoconjugates and Biosensors by providing customized design and production services for applications such as:

• Functionalization of nanosystems.
• Functionalization of implants and prosthesis.
• Tissue regenerative processes.
• Surfaces functionalization.

• All
• Biomol. Product.

Services

• U1-S01. Molecular Cloning (Biomolecules production)
• U1-S02. Bioproduction of proteins
• U1-S03. Proteins purification
• U1-S04. Consultancy in protein production
• U1-S05. Training courses in protein production (Biomolecules production)
• U1-S06. Criopreservation
• U2-S01. Scientific and technical support
• U2-S02. Hapten design and synthesis
• U2-S03. Preparation of Bioconjugates and Molecular Probes
• U2-S04. Polyclonal Antibody Production
• U2-S05. Monoclonal Antibody development
• U2-S06. In vitro antibody production
• U2-S07. Antibody purification
• U2-S08. Inmunochemical methods development
• U28-S07. Transmission Electron Microscopy (TEM)
• U29-S01. Synthesis of oligonucleotides and characterization (On-site & Remote). OUTSTANDING
• U29-S02. Modification of oligonucleotides. (Remote) OUTSTANDING
• U29-S03. Special nucleotides for oligonucleotide synthesis. (Remote) OUTSTANDING
• U3-S01. Synthesis of peptides and characterisation (On-site&Remote) OUTSTANDING
• U3-S02. Post synthesis peptide modification (On-site&Remote) OUTSTANDING
• U3-S03. Special amino acids for peptidomimetics synthesis (Remote) OUTSTANDING
• U3-S04. Peptide libraries (Remote) OUTSTANDING

Equipment

• U1.E01. 2 and 7 liter bioreactors for bio production
• U1.E02. 10 liter WAVE bioreactor for insect cells
• U1.E03. Incubator shaker with cooling unit for insect cells suspension cultures
• U1.E04. FPLC ÄKTA Chromatography systems for purification
• U1.E05. Tangential filtration Unit for purification
• U2-E01. Cell culture laboratory for hybridoma production.
• U2-E02. HiClass II Type A2 Biological Safety Cabinet (2 units)
• U2-E03. Inverted Microscope Leica DM IL LED with CCD camera
• U2-E04. CO2 cell culture incubator with UV contamination control (2 units)
• U2-E05. AKTA Prime FPLC system for purification of proteins
• U2-E06 Tangential Flow Filtration System (KrosFlo® Research Iii)
• U2-E07. Laboratory fully equipped for immunochemical methods.
• U2-E08. Laboratory perfectly equipped for chemical synthesis (to hapten synthesis)
• U2-E09. Animal facility.
• U20-E04. General laboratory equipment
• U29-E01. Automatic synthesizer.
• U29-E02. High-performance liquid chromatography (HPLC) systems with a diode array detector
• U29-E03. Speed-Vac evaporators
• U29-E04. UV spectrophotometer equipped with a Peltier temperature gradient.
• U29-E05. Spectrofluorimeter equipped with a Peltier temperature gradient.
• U29-E06. UV-Visible and luminometer Reader, multidetection system.
• U29-E07. Electrophoresis apparatus with several vertical and horizontal cuvettes.
• U3-E01. Automatic synthesizer
• U3-E02. High-performance liquid chromatography (HPLC) systems with a diode array detector.
• U3-E03. High-performance liquid chromatography (HPLC) system with dual-wavelength UV detector
• U3-E04. High-performance liquid chromatography (HPLC -MS) system with a diode array detector and coupled to a mass spectrometer
• U3-E05. Bohdan miniblocks
• U3-E06. Lyophilizers and SpeedVac evaporators
• U3-E07. System for acidolactic cleavage (Boc/Bzl strategy), UNIQUE IN SPAIN
• U3-E08. Amino acid analyzer and MALDI -TOF for characterization
• U3-E09. Microwave peptide synthesizer