Development of animal models of disease in large animals
Our experimental centre offers a service for the development of animal models of disease in large animals, providing a specialized platform for the advance of biomedical research. We are dedicated on creating preclinical models that accurately mimic human diseases in animals like pigs and sheeps, with the goal of facilitating the study of complex diseases and the assessment of new therapies.
We work with researchers to design and develop animal models, tailored to their specific needs. From the selection of the right animal to the methodology of disease induction, we ensure to create relevant and reliable models.
Customer benefits
Our institution is certified by the Spanish Agency of Medicines and Sanitary Products for a wide variety variety of studies like “Dosage of problem substance and non clinical sampling“, “Biocompatibility studies of sanitary products“, “In vivo Toxicity“, “Tolerance“ and “Pharmacodinamycs“. In addition, we are certified with ISO-9001 and Good Laboratory Practices (BPL).
Target customer
The development of animal models of disease in large animals of our institution serves a wide variety of clients, including academic researchers, pharmaceutical and biotechnological companies, medical devices companies, other research centres, regulatory agencies, etc. These clients need relevant and reliable animal models to conduct research and preclinical evaluation.
Additional information
Selected publications:
- Blanco-Blázquez V, Báez-Díaz C, Sánchez-Margallo FM, Torrescusa A, Vela FJ, Abellán E, Crisóstomo V. Swine Models of Aneurysmal Diseases for Training and Research. J Vis Exp. 2022 Mar 23;(181).
- Sun F, Báez-Díaz C, Sánchez-Margallo FM. Canine prostate models in preclinical studies of minimally invasive interventions: part I, canine prostate anatomy and prostate cancer models. Transl Androl Urol. 2017 Jun;6(3):538-546.
- Usón Gargallo J, Sánchez Margallo FM, Díaz-Güemes Martín-Portugués I, Loscertales Martín de Agar B, Soria Gálvez F, Pascual Sánchez-Gijón S. Modelos experimentales en la cirugía laparoscópica urológica [Animal models in urological laparoscopic training]. Actas Urol Esp. 2006 May;30(5):443-50.