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U3-S01. Synthesis of peptides and characterisation (On-site&Remote) OUTSTANDING

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20 May15:33pm
Nanbiosis
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Synthesis of peptides and characterisation (On-site&Remote) OUTSTANDING

Peptide production on various scales from mg (scale: 10 mg, 50 mg and 100 mg) and grams.
Synthesis of peptides containing phosphorylated amino acids, acylated or methylated side chains (lysine) or non-natural amino acids.
Peptides can be delivered as synthesis crudes (without purification) and purified (≥95% by HPLC).
Peptides are characterized by HPLC and HPLC-MS

Customer benefits

  • Extensive experience on peptide synthesis.
  • Experience in difficult sequences.
  • Control quality at different synthesis points.
  • Capability to design diverse synthesis strategies and purification
  • Development of peptide synthesis methodology.

Target customer

  • Research groups (drug delivery, molecular biology, pharmacology, nanotechnology, biotechnology)
  • Companies (biotech and pharma companies).

References

  • Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice. Sanz-Gonzalez, Alba; Cozar-Castellano, Irene; Broca, Christophe ; Sabatier, Julia; Acosta, Gerardo A. ; Royo, Miriam ; Hernando-Munoz, Carla; Torroba, Tomas ; Perdomo, German ; Merino, Beatriz. Diabetes, Obesity and Metabolism (2023), 25, 3268-3278.
  • Amide Formation: Choosing the Safer Carbodiimide in Combination with OxymaPure to Avoid HCN Release. Manne, Srinivasa Rao; Luna, Omar; Acosta, Gerardo A.; Royo, Miriam ; El-Faham, Ayman ; Orosz, Gyorgy; de la Torre, Beatriz G. ; Albericio, Fernando. Organic Letters (2021), 23, 6900-6904.
  • Carbosilane Dendron-Peptide Nanoconjugates as Antimicrobial Agents
  • By: Fernandez, Jael; Acosta, Gerardo; Pulido, Daniel; Maly, Marek; Copa-Patino, Jose L.; Soliveri, Juan; Royo, Miriam; Gomez, Rafael; Albericio, Fernando; Ortega, Paula; de la Mata, F. Javier. Molecular Pharmaceutics (2019), 16, 2661-2674.
  • Optimized Stepwise Synthesis of the API Liraglutide Using BAL Resin and Pseudoprolines. Carbajo, Daniel; El-Faham, Ayman; Royo, Miriam; Albericio, Fernando. ACS Omega (2019), 4, 8674-8680

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